Unveiling Sex-Based Differences in the Effects of Alcohol Abuse: A Comprehensive Functional Meta-Analysis of Transcriptomic Studies

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Unveiling Sex-Based Differences in the Effects of Alcohol Abuse: A Comprehensive Functional Meta-Analysis of Transcriptomic Studies

The abuse of alcohol, one of the well-liked psychoactive substances, may cause a number of pathological and psychological penalties, together with alcohol use dysfunction (AUD). An impaired capability to cease or management alcohol consumption regardless of opposed well being or social penalties characterize AUD. Whereas AUDs predominantly happen in males, rising proof suggests the existence of distinct cognitive and organic penalties of alcohol dependence in ladies. The molecular and physiological mechanisms taking part in these differential results stay unknown. Transcriptomic know-how permits the detection of the organic mechanisms accountable for such sex-based variations, which helps the following improvement of novel personalised therapeutics to deal with AUD.

We performed a scientific evaluate and meta-analysis of transcriptomics research concerning alcohol dependence in people with illustration from each sexes. For every examine, we processed and analyzed transcriptomic information to acquire a purposeful profile of pathways and organic capabilities after which built-in the ensuing information by meta-analysis to characterize any sex-based transcriptomic variations related to AUD.

International outcomes of the transcriptomic evaluation revealed the affiliation of decreased tissue regeneration, embryo malformations, altered intracellular transport, and elevated charge of RNA and protein substitute with feminine AUD sufferers. In the meantime, our evaluation indicated that elevated inflammatory response and blood stress and a discount in DNA restore capabilities are related to male AUD sufferers. In abstract, our purposeful meta-analysis of transcriptomic research gives proof for differential organic mechanisms of AUD sufferers of differing intercourse.

The sector of artificial biology heralds a brand new period in our relationship with nature, as organisms are engineered to satisfy human targets. However little consideration has been paid to potential cognitive constraints on reasoning about such applied sciences. Throughout 4 research with American adults (N = 649), the current analysis investigates the proposal that essentialist reasoning and ethical purity issues conspire to form danger assessments of engineered organisms. Ethical purity issues however not ethical hurt issues predict ethical wrongness judgments of including a overseas gene to a plant (Research 1, 2 & 4), in addition to assessments of danger (Research 1 and a couple of), and danger of hurt from consuming (Examine 4).

Including a gene from a taxonomically distant organism is taken into account extra morally flawed (Research 2, Three and 4), extra dangerous (Research 2 & 3), and extra dangerous to eat (Examine 4), than including both a gene from an identical organism or a new-to-nature gene. Assessments of the chance of gene unfold comply with a special sample, with the new-to-nature gene thought-about most secure (Examine 4). The findings help the proposal that gene change is reasoned about as essence change that threatens notions of ethical purity, with direct implications for sure kinds of danger perceptions (consuming), however not others (gene unfold).

Modeling a Cognitive Transition on the Origin of Cultural Evolution Utilizing Autocatalytic Networks

Autocatalytic networks have been used to mannequin the emergence of self-organizing construction able to sustaining life and present process organic evolution. Right here, we mannequin the emergence of cognitive construction able to present process cultural evolution. Psychological representations (MRs) of information and experiences play the function of catalytic molecules, and interactions amongst them (e.g., the forging of latest associations) play the function of reactions and end in representational redescription. The method tags MRs with their supply, that’s, whether or not they had been acquired by way of social studying, particular person studying (of pre-existing info), or inventive thought (ensuing within the era of latest info). This makes it doable to mannequin how cognitive construction emerges and to hint lineages of cumulative tradition step-by-step.
Unveiling Sex-Based Differences in the Effects of Alcohol Abuse: A Comprehensive Functional Meta-Analysis of Transcriptomic Studies
We develop a proper illustration of the cultural transition from Oldowan to Acheulean instrument know-how utilizing Reflexively Autocatalytic and Meals set generated (RAF) networks. In contrast to extra primitive Oldowan stone instruments, the Acheulean hand axe required not solely the capability to examine and convey into being one thing that didn’t but exist, however hierarchically structured thought and motion, and the era of latest MRs: the ideas EDGING, THINNING, SHAPING, and a meta-concept, HAND AXE. We present how this constituted a key transition towards the emergence of semantic networks that had been self-organizing, self-sustaining, and autocatalytic, and we focus on how such networks replicated by way of social interplay. The mannequin gives a promising method to unraveling one of many biggest anthropological mysteries: that of why improvement of the Acheulean hand axe was adopted by over one million years of cultural stasis.

Starting of life ethics on the daybreak of a brand new period of genome modifying: are bioethical precepts and fast-evolving biotechnologies irreconcilable?

The superb and virtually unimaginable advances which have unfolded over the previous a long time in biotechnologies (heritable germline modifying particularly) have introduced bioethical points to the forefront, sparking public debate and growing consideration worldwide. Such mind-blowing progress has already resulted in main enchancment and enhancements for people, and holds the potential for much more. Expertise and bioengineering have begun to take over within the life sciences trade.
Man’s capability to genetically engineer the organic world is nothing in need of mind-boggling in its present magnitude, and will even evolve, in a not too distant future, into makes an attempt to fuse man and machine right into a cohesive bioengineered entity; a “tremendous human being”, endowed with enhanced cognitive and bodily capabilities and impervious to illness, could also be not too far down the highway. That won’t come with out caveats, nevertheless.

Recombinant purified human GST-mu (GST-M1) protein biologically active
GSTM25-R-100 100 ug
EUR 1000.8

Recombinant purified human GST-mu (GST-M1) protein biologically active
GSTM25-R-25 25 ug
EUR 416.4

Recombinant purified human GST-pi (GST-P1) protein biologically active
GSTP35-R-100 100 ug
EUR 1000.8

Recombinant purified human GST-pi (GST-P1) protein biologically active
GSTP35-R-25 25 ug
EUR 416.4

Recombinant (E. coli) purified Human Angiogenin protein, biologically active
ANGN15-R-50 50 ug
EUR 927.6

Purified (CHO cells) Recombinant Human BMP7 protein, Biologically active
BMP75-R-10 10 ug
EUR 1074

Recombinant purified human GST-alpha (GST-A1) protein biologically active
GSTA15-R-100 100 ug
EUR 1000.8

Recombinant purified human GST-alpha (GST-A1) protein biologically active
GSTA15-R-25 25 ug
EUR 416.4

Recombinant purified Human Endostatin protein (P. Pastoris) biologically active
ENST13-R-100 100 ug
EUR 562.8

Recombinant purified Human Endostatin protein (P. Pastoris) biologically active
ENST13-R-1000 1000 ug
EUR 1951.2

Recombinant purified Human Endostatin protein (P. Pastoris) biologically active
ENST13-R-250 250 ug
EUR 854.4

Recombinant purified human GST-T1-1 (GST T1-1) protein biologically active
GSTT45-R-100 100 ug
EUR 1000.8

Recombinant purified human GST-T1-1 (GST T1-1) protein biologically active
GSTT45-R-25 25 ug
EUR 416.4

Mouse Recombinant Purified Noggin-Fc protein, biologically active
NOGN25-R-10 10 ug
EUR 416.4

Mouse Recombinant Purified Noggin-Fc protein, biologically active
NOGN25-R-25 25 ug
EUR 781.2

Recombinant purified Human Heme Oxygenase 2 (HO-2) protein (biologically active)
HO25-R-25 25 ug
EUR 416.4

Recombinant purified human GST-alpha 3 (GST A3-3) protein biologically active
GSTA35-R-100 100 ug
EUR 1000.8

Recombinant purified human GST-alpha 3 (GST A3-3) protein biologically active
GSTA35-R-25 25 ug
EUR 416.4

Purified (E.Coli) Recombinant Human BMP2 protein, Biologically active, Carrier free
BMP25-R-10 10 ug
EUR 1074

Mouse Recombinant Purified Noggin protein (E. coli), biologically active
NOGN26-R-20 20 ug
EUR 781.2

Mouse Recombinant Purified Noggin protein (E. coli), biologically active
NOGN26-R-5 5 ug
EUR 343.2

Recombinant purified Rat Heme Oxygenase 1 (HO-1) protein (biologically active)
HO15-R-25 25 ug
EUR 416.4

Human Recombinant (E.Coli) Angiostatin Kringles 1-3 purified protein biologically active
ANKR131-R-250 250 ug
EUR 927.6

Human Recombinant (E.Coli) Angiostatin Kringles 1-3 purified protein biologically active
ANKR131-R-50 50 ug
EUR 270

Recombinant purified Mouse Endostatin protein (P. Pastoris) biologically active, low endotoxin
ENST15-R-100 100 ug
EUR 562.8

Recombinant purified Mouse Endostatin protein (P. Pastoris) biologically active, low endotoxin
ENST15-R-250 250 ug
EUR 854.4

Purified Recombinant Human BMP-13 (CDMP-2/GDF-6), Biologically active, Carrier free
BMP135-R-10 10 ug
EUR 489.6

Purified Recombinant Human BMP-13 (CDMP-2/GDF-6), Biologically active, Carrier free
BMP135-R-50 50 ug
EUR 1074

Purified Recombinant Human BMP-14 (CDMP-1/GDF-5), Biologically active, Carrier free
BMP145-R-10 10 ug
EUR 489.6

Purified Recombinant Human BMP-14 (CDMP-1/GDF-5), Biologically active, Carrier free
BMP145-R-50 50 ug
EUR 1074

Recombinant (E. coli), purified, Human beta-Defensin 4 (BD-4/hBD-4) full length protein (50 aa), biologically active
HBD45-R-20 20 ug
EUR 708

Recombinant (E. coli), purified, Human beta-Defensin 4 (BD-4/hBD-4) full length protein (50 aa), biologically active
HBD45-R-5 5 ug
EUR 343.2

Recombinant (E.Coli) purified human Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active
TNFA15-R-10 10 ug
EUR 270

Recombinant (E. coli), purified, Mouse beta-Defensin 2 (BD-2/mBD-2) full length protein, biologically active
MBD25-R-10 10 ug
EUR 548.4

Recombinant (E.Coli), purified, Human beta-Defensin 3 (BD-3/hBD-3, full length peptide (45 aa), biologically active
HBD37-R-10 10 ug
EUR 416.4

Recombinant (E.Coli), purified, Human beta-Defensin 3 (BD-3/hBD-3, full length peptide (45 aa), biologically active
HBD37-R-100 100 ug
EUR 2617.2

Recombinant (E.Coli), purified, Human beta-Defensin 3 (BD-3/hBD-3, full length peptide (45 aa), biologically active
HBD37-R-1000 1000 ug
EUR 7221.6

Recombinant (E.Coli) purified rat Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active
TNFA25-R-5 5 ug
EUR 270

Recombinant (E.Coli) purified mouse Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active
TNFA35-R-5 5 ug
EUR 270

Recombinant (E. coli), purified, Human beta-Defensin 1 (BD-1/hBD-1) full length peptide (36 aa), biologically active
HBD17-R-10 10 ug
EUR 460.8

Recombinant (E. coli), purified, Human beta-Defensin 1 (BD-1/hBD-1) full length peptide (36 aa), biologically active
HBD17-R-100 100 ug
EUR 2324.4

Recombinant (E. coli), purified, Human beta-Defensin 1 (BD-1/hBD-1) full length peptide (36 aa), biologically active
HBD17-R-1000 1000 ug
EUR 6637.2

Recombinant (E. coli), purified, Human beta-Defensin 2 (BD-2/hBD-2) full length peptide (41 aa), biologically active
HBD25-R-10 10 ug
EUR 416.4

Recombinant (E. coli), purified, Human beta-Defensin 2 (BD-2/hBD-2) full length peptide (41 aa), biologically active
HBD25-R-100 100 ug
EUR 2617.2

Recombinant (E. coli), purified, Human beta-Defensin 2 (BD-2/hBD-2) full length peptide (41 aa), biologically active
HBD25-R-1000 1000 ug
EUR 7221.6

Recombinant (E.Coli) purified porcine Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active
TNFA36-R-5 5 ug
EUR 270

Recombinant (E.Coli) purified human Tumor Necrosis Factor-Alpha Variant (TNF-alpha variant, 151-aa), biologically active
TNFA16-R-10 10 ug
EUR 270

Human Calcineurin A-subunit protein biologically active
CALNA15-R 1000 U
EUR 416.4

Human Recombinant VEGF121 Protein (Sf9), biologically active
VEGF24-R-10 10 ug
EUR 534

Human Recombinant VEGF121 Protein (Sf9), biologically active
VEGF24-R-100 100 ug
EUR 2910

Human Recombinant VEGF165 Protein (Sf9), biologically active
VEGF27-R-10 10 ug
EUR 534

Human Recombinant VEGF165 Protein (HEK), biologically active
VEGF27-R-100 100 ug
EUR 2910

Human Recombinant VEGF165 Protein (Sf9), biologically active
VEGF27-R-1000 1000 ug
EUR 11022

Human Recombinant VEGF121 Protein (E.Coli), biologically active
VEGF25-R-10 10 ug
EUR 534

Human Recombinant VEGF121 Protein (E.Coli), biologically active
VEGF25-R-100 100 ug
EUR 2910

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-10 10 ug
EUR 534

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-100 100 ug
EUR 2690.4

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-1000 1000 ug
EUR 11022

Human Pancreatic Lipase (partially pure) biologically active
PLIP15-N 10 U
EUR 343.2

Human Recombinant EG-VEGF Protein (84aa, E. Coli), biologically active
VEGF36-R-100 100 ug
EUR 2389.2

Human Recombinant EG-VEGF Protein (84aa, E. coli), biologically active
VEGF36-R-20 20 ug
EUR 927.6

Human Recombinant EG-VEGF Protein (84aa, E. coli), biologically active
VEGF36-R-5 5 ug
EUR 388.8

Lipase, Human Pancreas (biologically active) antigen grade (.95% pure)
PLIP15-N-10 10 ug
EUR 343.2

Rat Recombinant VEGF152 (VEGF-C) Protein (Sf9), biologically active
VEGF31-R-10 10 ug
EUR 534

Rat Recombinant VEGF129 (VEGF-C) Protein (Sf9), biologically active
VEGF32-R-10 10 ug
EUR 534

Rat Recombinant VEGF129 (VEGF-C) Protein (Sf9), biologically active
VEGF32-R-100 100 ug
EUR 2910

Rat Recombinant VEGF164 (VEGF-A) Protein (E.Coli), biologically active
VEGF33-R-10 10 ug
EUR 534

Rat Recombinant VEGF164 (VEGF-A) Protein (E.Coli), biologically active
VEGF33-R-100 100 ug
EUR 2973.6

Mouse Recombinant VEGF164 (VEGF-A) Protein (Sf9), biologically active
VEGF34-R-10 10 ug
EUR 534

Mouse Recombinant VEGF164 (VEGF-A) Protein (Sf9), biologically active
VEGF34-R-100 100 ug
EUR 2973.6

Mouse Recombinant VEGF165 (VEGF-A) Protein (E.Coli), biologically active
VEGF35-R-10 10 ug
EUR 534

Mouse Recombinant VEGF165 (VEGF-A) Protein (E.Coli), biologically active
VEGF35-R-100 100 ug
EUR 2690.4

Recombinant (E. coli) human placenta growth factor-1 (PLGF-1) Protein (>97%), biologically active
PLGF15-R-25 25 ug
EUR 634.8

Recombinant (E. coli) human placenta growth factor-1 (PLGF-1) Protein (>97%), biologically active
PLGF15-R-5 5 ug
EUR 270

Recombinant (HEK) Human VEGFR1/FLT1 Protein (1-328aa-IgG1-Fc, >95%, ~67 kda, low endotoxin), biologically active
VEGFR15-R-10 10 ug
EUR 416.4

Recombinant (HEK) Human VEGFR2/Kdr/FLK1 Protein (1-764aa-IgG-Fc, >95%, ~160 kda, low endotoxin), biologically active
VEGFR25-R-10 10 ug
EUR 416.4

Human Recombinant Transforming Growth Factor-alpha (TGF-alpha), biologically active
TGFA15-R-100 100 ug
EUR 634.8

Human Recombinant Transforming Growth Factor-alpha (TGF-alpha), biologically active
TGFA15-R-1000 1000 ug
EUR 4225.2

Human Recombinant Transforming Growth Factor-alpha (TGF-alpha), biologically active
TGFA15-R-20 20 ug
EUR 270

Recombinant (plant) Human Apotransferrin, Tissue Culture Grade (animal free, biologically active, >95% pure
TF27-N-100 100 mg
EUR 270

Recombinant (plant) Human Apotransferrin, Tissue Culture Grade (animal free, biologically active, >95% pure
TF27-N-1000 100 mg
EUR 781.2

Purified Human Plasminogen protein W. Blot Positive control
PLMN11-C 100 ul
EUR 343.2

Recombinnat purified Human Plasminogen Activator Inhibitor 1 (PAI-1) protein (his-tag) control for ELISA
PAI21-R-25 25 ug
EUR 343.2

Recombinnat purified Human Plasminogen Activator Inhibitor 1 (PAI-1) protein (his-tag) control for Western blot
PAI21-C 100 ul
EUR 343.2

Human Plasminogen (Plg) Protein (Active)
20-abx655799
  • EUR 661.20
  • EUR 309.60
  • EUR 1930.80
  • EUR 777.60
  • EUR 493.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen (Plg) Protein (Active)
20-abx655800
  • EUR 661.20
  • EUR 309.60
  • EUR 1930.80
  • EUR 777.60
  • EUR 493.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Plasminogen (Plg) Protein (Active)
20-abx651431
  • EUR 1195.20
  • EUR 427.20
  • EUR 3934.80
  • EUR 1446.00
  • EUR 828.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Active Plasminogen (Plg)
4-APB236Hu01
  • EUR 468.36
  • EUR 248.40
  • EUR 1426.37
  • EUR 555.46
  • EUR 990.91
  • EUR 388.80
  • EUR 3385.92
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Active Plasminogen (Plg) expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Plasminogen (Plg)
4-APB236Hu51
  • EUR 468.36
  • EUR 248.40
  • EUR 1426.37
  • EUR 555.46
  • EUR 990.91
  • EUR 388.80
  • EUR 3385.92
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Plasminogen expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Plasminogen (Plg)
4-APB236Ra01
  • EUR 872.64
  • EUR 357.60
  • EUR 2942.40
  • EUR 1060.80
  • EUR 2001.60
  • EUR 660.00
  • EUR 7176.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Plasminogen expressed in: E.coli

Human Plasminogen Activator Inhibitor 2 (PAI2) Protein (Active)
20-abx655801
  • EUR 1296.00
  • EUR 477.60
  • EUR 4318.80
  • EUR 1579.20
  • EUR 895.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Active Plasminogen Activator, Tissue (tPA)
4-APA525Mu01
  • EUR 1025.32
  • EUR 398.40
  • EUR 3514.94
  • EUR 1251.65
  • EUR 2383.30
  • EUR 762.00
  • EUR 8607.36
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Plasminogen Activator, Tissue expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Recombinant purified, human NFkB-p65 protein, active
NFKB651-R-5 5 ug
EUR 781.2

Purified Diphtheria Toxin protein (active)
DTOX18-N-250 250 ug
EUR 489.6

Purified, recombinant Human TACE control protein (active)
TACE15-R-10 10 ug
EUR 854.4

Recombinant purified, human Akt-2/PKB-beta protein, active
AKT25-R-10 10 ug
EUR 416.4

Recombinant purified human Akt-1/PKB-alpha protein (active)
AKT15-R-15 15 ug
EUR 1074

Recombinant purified, human Akt-3/PKB-gamma protein, active
AKT35-R-5 5 ug
EUR 416.4

Human Plasminogen Activator, Tissue (tPA) Protein
20-abx068565
  • EUR 794.40
  • EUR 326.40
  • EUR 2448.00
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen Activator, Tissue (tPA) Protein
20-abx068567
  • EUR 794.40
  • EUR 326.40
  • EUR 2448.00
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen Activator, Urokinase (uPA) Protein
20-abx654747
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen Activator Inhibitor 1 (PAI1) Protein
20-abx068561
  • EUR 744.00
  • EUR 326.40
  • EUR 2230.80
  • EUR 878.40
  • EUR 543.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen Activator Inhibitor 2 (PAI2) Protein
20-abx068562
  • EUR 811.20
  • EUR 326.40
  • EUR 2481.60
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen Activator Inhibitor 1 (PAI1) Protein
abx670216-10ug 10 ug
EUR 661.2

Purified Human Placenta Dipeptidyl Peptidase IV (DPP4), active
DPP48-N-1 10 ug
EUR 416.4

Human Plasminogen Protein
abx060920-1mg 1 mg
EUR 460.8

Recombinant purified human Akt-1/PKB-alpha protein (PHD deletion 1-116 active)
AKT16-R 1 U
EUR 562.8

Recombinant (E.Coli) purified, human Protein Kinase Akt1/PKB alpha (PRKBA/PKB) protein, active
PAKT18-R-5 5 ug
EUR 634.8

Human Plasminogen Activator, Urokinase Receptor (uPAR) Protein
20-abx068569
  • EUR 661.20
  • EUR 292.80
  • EUR 1914.00
  • EUR 777.60
  • EUR 493.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen Activator, Urokinase Receptor (uPAR) Protein
20-abx068572
  • EUR 661.20
  • EUR 292.80
  • EUR 1914.00
  • EUR 777.60
  • EUR 493.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen Activator, Urokinase Receptor (uPAR) Protein
20-abx068573
  • EUR 661.20
  • EUR 292.80
  • EUR 1914.00
  • EUR 777.60
  • EUR 493.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant (E.coli) purified human AKT1(Akt-1/PKB-alpha/RAC-alpha) protein, active
AKT17-R-10 10 ug
EUR 416.4

Recombinant purified (E. coli, >80%, GST-tag) human NFkB-p50 protein, active
NFKB502-R-5 5 ug
EUR 489.6

tPA Tissue Plasminogen Activator Human Recombinant Protein
PROTP00750 Regular: 100ug
EUR 411.6
Description: Tissue Plasminogen Activator Human Recombinant produced in CHO cells is a single, glycosylated polypeptide chain containing 527 amino acids and having a molecular mass of 59008.71 Dalton. tPA is a serine protease enzyme that converts plasminogen to plasmin. ;The tPA is purified by proprietary chromatographic techniques.

SERPINE1 Plasminogen Activator Inhibitor-1 Human protein
PROTP05121 Regular: 10ug
EUR 380.4
Description: Constitutively active human plasminogen activator inhibitor 1, stable mutant 14-1B having a Molecular mass of 43 kDa. This human form of SERPINE1 contains the following four mutations: K154T, Q139L, M354I and N150H. These mutations combine to confer great stability to the otherwise labile molecule essentially locking it into the active conformation. ;The SERPINE1 is purified by proprietary chromatographic techniques.

Recombinant (HEK) Purified human Transferrin receptor (TfR1/CD71) protein (his-tag), active
TFR19-R-25 25 ug
EUR 343.2

Recombinant (E. coli) purified Firefly Luciferase protein, active
LUCF15-R 250 ug
EUR 336

Human Plasminogen activator inhibitor 1 RNA- binding protein, SE
ELI-23301h 96 Tests
EUR 988.8

Pig Plasminogen Activator, Tissue (tPA) Protein
20-abx167537
  • EUR 895.20
  • EUR 360.00
  • EUR 2815.20
  • EUR 1078.80
  • EUR 644.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Plasminogen Activator, Tissue (tPA) Protein
20-abx167694
  • EUR 861.60
  • EUR 343.20
  • EUR 2665.20
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

tPA Human, Tissue Plasminogen Activator Human Recombinant Protein, Sf9
PROTP00750-1 Regular: 5ug
EUR 380.4
Description: tPA Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 545 amino acids (24-562 a.a) and having a molecular mass of 61.3kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).;tPA is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

Human Tissue Plasminogen Activator
90248-A 20 µg
EUR 130
Description: Recombinant tPA is a disulfide-linked monomer protein consisting 527 amino acid residue subunits. and migrates due to glycosylation as an approximately 60kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Tissue Plasminogen Activator mature chain was expressed in CHO cells.

Human Tissue Plasminogen Activator
90248-B 100 µg
EUR 205
Description: Recombinant tPA is a disulfide-linked monomer protein consisting 527 amino acid residue subunits. and migrates due to glycosylation as an approximately 60kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Tissue Plasminogen Activator mature chain was expressed in CHO cells.

Recombinant, purified, Human O6-methylguanine-DNA-Methyl transferase (MGMT) protein (active)
MGMT15-R-10 10 ug
EUR 781.2

Recombinant, purified, Human O6-methylguanine-DNA-Methyl transferase (MGMT) protein (active)
MGMT15-R-5 5 ug
EUR 489.6

Recombinant purified Human Klotho protein (NS0 cells, His-tag; Alpha form; EC domain), active
KL16-R 5 ug
EUR 343.2

Mouse Plasminogen Activator, Tissue (tPA) Protein
20-abx068566
  • EUR 861.60
  • EUR 343.20
  • EUR 2698.80
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Plasminogen Activator, Urokinase (uPA) Protein
20-abx168541
  • EUR 878.40
  • EUR 343.20
  • EUR 2749.20
  • EUR 1045.20
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Pig Plasminogen Activator, Urokinase (uPA) Protein
20-abx068568
  • EUR 944.40
  • EUR 360.00
  • EUR 2983.20
  • EUR 1128.00
  • EUR 661.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Cow Plasminogen Activator, Urokinase (uPA) Protein
20-abx654749
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen activator ELISA kit
E01P0684-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Plasminogen activator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Plasminogen activator ELISA kit
E01P0684-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Plasminogen activator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Plasminogen activator ELISA kit
E01P0684-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Plasminogen activator in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human plasminogen activator Elisa Kit
ELA-E1285h 96 Tests
EUR 988.8

Human Plasminogen (Plg) Protein
20-abx068558
  • EUR 427.20
  • EUR 260.40
  • EUR 1161.60
  • EUR 526.80
  • EUR 343.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen (Plg) Protein
20-abx068560
  • EUR 427.20
  • EUR 260.40
  • EUR 1161.60
  • EUR 526.80
  • EUR 343.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Plasminogen (Plg) Protein
20-abx651557
  • EUR 944.40
  • EUR 360.00
  • EUR 2983.20
  • EUR 1128.00
  • EUR 661.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Plasminogen Activator, Urokinase (uPA) Protein
20-abx167429
  • EUR 844.80
  • EUR 343.20
  • EUR 2614.80
  • EUR 1011.60
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant (E.coli) purified Human Granulocyte Colony Stimulating Factor (GCSF, G-CSF) protein, active
GCSF16-R 10 ug
EUR 460.8

Human recombinant purified matrilysin/MMP7 (matrix metalloproteinase 7) biolgoically active
MMP71-R 25 ug
EUR 315.6

Rabbit Plasminogen Activator, Urokinase (uPA) Protein
20-abx654751
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Plasminogen protein
30-AP27 1 mg
EUR 352.8
Description: Purified native Human Plasminogen protein

SERPINE1 Plasminogen Activator Inhibitor-1 Human Recombinant Protein
PROTP05121-1 Regular: 25ug
EUR 380.4
Description: SERPINE1 Human Recombinant fused to N-terminal His-Tag produced in E.Coli is a single, non-glycosylated polypeptide chain containing 400 amino acids (24-402) and having a molecular mass of 45 kDa.;The SERPINE1 is purified by proprietary chromatographic techniques.

Chicken Plasminogen Activator, Urokinase (uPA) Protein
20-abx654750
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Plasminogen Activator Inhibitor 2 (PAI2) Protein
20-abx068564
  • EUR 895.20
  • EUR 360.00
  • EUR 2798.40
  • EUR 1062.00
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Plasminogen Activator Inhibitor 1 (PAI1) Protein
20-abx167598
  • EUR 828.00
  • EUR 343.20
  • EUR 2548.80
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

TPA (36-310)Human Tissue Plasminogen Activator (36-310 a.a.) Human Recombinant Protein
PROTP00750-3 Regular: 5ug
EUR 380.4
Description: TPA Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 284 amino acids (36-310a.a.) and having a molecular mass of 32.0kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).;TPA is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.

Human Plasminogen Activator Inhibitor-1
7-03571 2µg Ask for price

Human Plasminogen Activator Inhibitor-1
7-03572 10µg Ask for price

Human Plasminogen Activator Inhibitor-1
7-03573 1mg Ask for price

Human Plasminogen Activator Inhibitor-1
RP-1471 10 ug
EUR 343.2

TPA (311-562) Tissue Plasminogen Activator (311-562 a.a.) Human Recombinant Protein
PROTP00750-2 Regular: 10ug
EUR 380.4
Description: TPA Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 261 amino acids (311-562 a.a.) and having a molecular mass of 29.2kDa (Migrates at 28-40kDa on SDS-PAGE under reducing conditions).;TPA is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Human plasminogen activator,PLGA ELISA Kit
201-12-1192 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human plasminogen activator,PLGA ELISA Kit
CN-03441H1 96T
EUR 555.6

Human plasminogen activator,PLGA ELISA Kit
CN-03441H2 48T
EUR 374.4

Human plasminogen activator(PLGA)ELISA Kit
GA-E1208HM-48T 48T
EUR 346.8

Human plasminogen activator(PLGA)ELISA Kit
GA-E1208HM-96T 96T
EUR 559.2

Human plasminogen activator(PLGA)ELISA Kit
QY-E00914 96T
EUR 433.2

Human plasminogen activator,PLGA ELISA Kit
YLA1118HU-48T 48T
EUR 435

Human plasminogen activator,PLGA ELISA Kit
YLA1118HU-96T 96T
EUR 562.5

Mouse Plasminogen Activator Inhibitor 1 (PAI1) Protein
20-abx168332
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Plasminogen Activator Inhibitor 2 (PAI2) Protein
20-abx068563
  • EUR 844.80
  • EUR 343.20
  • EUR 2631.60
  • EUR 1011.60
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant purified, human Interleukin-1 alpha (IL-1 alpha), active
IL1A15-R-10 10 ug
EUR 416.4

Rabbit Plasminogen Activator Inhibitor 1 (PAI1) Protein
20-abx654742
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Monkey Plasminogen Activator Inhibitor 1 (PAI1) Protein
20-abx654743
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rabbit Plasminogen Activator Inhibitor 2 (PAI2) Protein
20-abx654745
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
The truth is, scientific developments at such an accelerated tempo have already negatively affected our cultural, moral, and authorized values and our capability to harness the alternatives and face the risks posed by such developments. As a matter of reality, science appears to persistently outpace public morals, ethics and policymaking, which requires a excessive diploma of warning and customary solutions.

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