The abuse of alcohol, one of the well-liked psychoactive substances, may cause a number of pathological and psychological penalties, together with alcohol use dysfunction (AUD). An impaired capability to cease or management alcohol consumption regardless of opposed well being or social penalties characterize AUD. Whereas AUDs predominantly happen in males, rising proof suggests the existence of distinct cognitive and organic penalties of alcohol dependence in ladies. The molecular and physiological mechanisms taking part in these differential results stay unknown. Transcriptomic know-how permits the detection of the organic mechanisms accountable for such sex-based variations, which helps the following improvement of novel personalised therapeutics to deal with AUD.
We performed a scientific evaluate and meta-analysis of transcriptomics research concerning alcohol dependence in people with illustration from each sexes. For every examine, we processed and analyzed transcriptomic information to acquire a purposeful profile of pathways and organic capabilities after which built-in the ensuing information by meta-analysis to characterize any sex-based transcriptomic variations related to AUD.
International outcomes of the transcriptomic evaluation revealed the affiliation of decreased tissue regeneration, embryo malformations, altered intracellular transport, and elevated charge of RNA and protein substitute with feminine AUD sufferers. In the meantime, our evaluation indicated that elevated inflammatory response and blood stress and a discount in DNA restore capabilities are related to male AUD sufferers. In abstract, our purposeful meta-analysis of transcriptomic research gives proof for differential organic mechanisms of AUD sufferers of differing intercourse.
The sector of artificial biology heralds a brand new period in our relationship with nature, as organisms are engineered to satisfy human targets. However little consideration has been paid to potential cognitive constraints on reasoning about such applied sciences. Throughout 4 research with American adults (N = 649), the current analysis investigates the proposal that essentialist reasoning and ethical purity issues conspire to form danger assessments of engineered organisms. Ethical purity issues however not ethical hurt issues predict ethical wrongness judgments of including a overseas gene to a plant (Research 1, 2 & 4), in addition to assessments of danger (Research 1 and a couple of), and danger of hurt from consuming (Examine 4).
Including a gene from a taxonomically distant organism is taken into account extra morally flawed (Research 2, Three and 4), extra dangerous (Research 2 & 3), and extra dangerous to eat (Examine 4), than including both a gene from an identical organism or a new-to-nature gene. Assessments of the chance of gene unfold comply with a special sample, with the new-to-nature gene thought-about most secure (Examine 4). The findings help the proposal that gene change is reasoned about as essence change that threatens notions of ethical purity, with direct implications for sure kinds of danger perceptions (consuming), however not others (gene unfold).
Modeling a Cognitive Transition on the Origin of Cultural Evolution Utilizing Autocatalytic Networks
Autocatalytic networks have been used to mannequin the emergence of self-organizing construction able to sustaining life and present process organic evolution. Right here, we mannequin the emergence of cognitive construction able to present process cultural evolution. Psychological representations (MRs) of information and experiences play the function of catalytic molecules, and interactions amongst them (e.g., the forging of latest associations) play the function of reactions and end in representational redescription. The method tags MRs with their supply, that’s, whether or not they had been acquired by way of social studying, particular person studying (of pre-existing info), or inventive thought (ensuing within the era of latest info). This makes it doable to mannequin how cognitive construction emerges and to hint lineages of cumulative tradition step-by-step.

We develop a proper illustration of the cultural transition from Oldowan to Acheulean instrument know-how utilizing Reflexively Autocatalytic and Meals set generated (RAF) networks. In contrast to extra primitive Oldowan stone instruments, the Acheulean hand axe required not solely the capability to examine and convey into being one thing that didn’t but exist, however hierarchically structured thought and motion, and the era of latest MRs: the ideas EDGING, THINNING, SHAPING, and a meta-concept, HAND AXE. We present how this constituted a key transition towards the emergence of semantic networks that had been self-organizing, self-sustaining, and autocatalytic, and we focus on how such networks replicated by way of social interplay. The mannequin gives a promising method to unraveling one of many biggest anthropological mysteries: that of why improvement of the Acheulean hand axe was adopted by over one million years of cultural stasis.
Starting of life ethics on the daybreak of a brand new period of genome modifying: are bioethical precepts and fast-evolving biotechnologies irreconcilable?
The superb and virtually unimaginable advances which have unfolded over the previous a long time in biotechnologies (heritable germline modifying particularly) have introduced bioethical points to the forefront, sparking public debate and growing consideration worldwide. Such mind-blowing progress has already resulted in main enchancment and enhancements for people, and holds the potential for much more. Expertise and bioengineering have begun to take over within the life sciences trade.
Man’s capability to genetically engineer the organic world is nothing in need of mind-boggling in its present magnitude, and will even evolve, in a not too distant future, into makes an attempt to fuse man and machine right into a cohesive bioengineered entity; a “tremendous human being”, endowed with enhanced cognitive and bodily capabilities and impervious to illness, could also be not too far down the highway. That won’t come with out caveats, nevertheless.
Mouse Recombinant Purified Noggin-Fc protein, biologically active |
NOGN25-R-25 |
Alpha Diagnostics |
25 ug |
EUR 651 |
Recombinant (E. coli) purified Human Angiogenin protein, biologically active |
ANGN15-R-50 |
Alpha Diagnostics |
50 ug |
EUR 773 |
Purified (CHO cells) Recombinant Human BMP7 protein, Biologically active |
BMP75-R-10 |
Alpha Diagnostics |
10 ug |
EUR 895 |
Recombinant purified Human Endostatin protein (P. Pastoris) biologically active |
ENST13-R-100 |
Alpha Diagnostics |
100 ug |
EUR 469 |
Recombinant purified Human Endostatin protein (P. Pastoris) biologically active |
ENST13-R-1000 |
Alpha Diagnostics |
1000 ug |
EUR 1626 |
Recombinant purified Human Endostatin protein (P. Pastoris) biologically active |
ENST13-R-250 |
Alpha Diagnostics |
250 ug |
EUR 712 |
Purified Human Angiostatin (Kringles 1-4) protein (>98%), biologically active |
ANST11-R |
Alpha Diagnostics |
100 ug |
EUR 347 |
Purified (E.Coli) Recombinant Human BMP2 protein, Biologically active, Carrier free |
BMP25-R-10 |
Alpha Diagnostics |
10 ug |
EUR 895 |
Recombinant purified human GST-alpha (GST-A1) protein biologically active |
GSTA15-R-100 |
Alpha Diagnostics |
100 ug |
EUR 834 |
Recombinant purified human GST-alpha (GST-A1) protein biologically active |
GSTA15-R-25 |
Alpha Diagnostics |
25 ug |
EUR 347 |
Recombinant purified human GST-mu (GST-M1) protein biologically active |
GSTM25-R-100 |
Alpha Diagnostics |
100 ug |
EUR 834 |
Recombinant purified human GST-mu (GST-M1) protein biologically active |
GSTM25-R-25 |
Alpha Diagnostics |
25 ug |
EUR 347 |
Recombinant purified human GST-pi (GST-P1) protein biologically active |
GSTP35-R-100 |
Alpha Diagnostics |
100 ug |
EUR 834 |
Recombinant purified human GST-pi (GST-P1) protein biologically active |
GSTP35-R-25 |
Alpha Diagnostics |
25 ug |
EUR 347 |
Mouse Recombinant Purified Noggin protein (E. coli), biologically active |
NOGN26-R-20 |
Alpha Diagnostics |
20 ug |
EUR 651 |
Mouse Recombinant Purified Noggin protein (E. coli), biologically active |
NOGN26-R-5 |
Alpha Diagnostics |
5 ug |
EUR 286 |
Human Recombinant (E.Coli) Angiostatin Kringles 1-3 purified protein biologically active |
ANKR131-R-250 |
Alpha Diagnostics |
250 ug |
EUR 773 |
Human Recombinant (E.Coli) Angiostatin Kringles 1-3 purified protein biologically active |
ANKR131-R-50 |
Alpha Diagnostics |
50 ug |
EUR 225 |
Recombinant purified Human Heme Oxygenase 2 (HO-2) protein (biologically active) |
HO25-R-25 |
Alpha Diagnostics |
25 ug |
EUR 347 |
Recombinant purified human GST-alpha 3 (GST A3-3) protein biologically active |
GSTA35-R-100 |
Alpha Diagnostics |
100 ug |
EUR 834 |
Recombinant purified human GST-alpha 3 (GST A3-3) protein biologically active |
GSTA35-R-25 |
Alpha Diagnostics |
25 ug |
EUR 347 |
Recombinant purified human GST-T1-1 (GST T1-1) protein biologically active |
GSTT45-R-100 |
Alpha Diagnostics |
100 ug |
EUR 834 |
Recombinant purified human GST-T1-1 (GST T1-1) protein biologically active |
GSTT45-R-25 |
Alpha Diagnostics |
25 ug |
EUR 347 |
Recombinant purified Mouse Endostatin protein (P. Pastoris) biologically active, low endotoxin |
ENST15-R-100 |
Alpha Diagnostics |
100 ug |
EUR 469 |
Recombinant purified Mouse Endostatin protein (P. Pastoris) biologically active, low endotoxin |
ENST15-R-250 |
Alpha Diagnostics |
250 ug |
EUR 712 |
Recombinant purified Rat Heme Oxygenase 1 (HO-1) protein (biologically active) |
HO15-R-25 |
Alpha Diagnostics |
25 ug |
EUR 347 |
Human Calcineurin A-subunit protein biologically active |
CALNA15-R |
Alpha Diagnostics |
1000 U |
EUR 347 |
Human Recombinant VEGF121 Protein (Sf9), biologically active |
VEGF24-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Human Recombinant VEGF121 Protein (Sf9), biologically active |
VEGF24-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2425 |
Human Recombinant VEGF121 Protein (E.Coli), biologically active |
VEGF25-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Human Recombinant VEGF121 Protein (E.Coli), biologically active |
VEGF25-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2425 |
Human Recombinant VEGF165 Protein (E.Coli), biologically active |
VEGF26-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Human Recombinant VEGF165 Protein (E.Coli), biologically active |
VEGF26-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2242 |
Human Recombinant VEGF165 Protein (E.Coli), biologically active |
VEGF26-R-1000 |
Alpha Diagnostics |
1000 ug |
EUR 9185 |
Human Recombinant VEGF165 Protein (Sf9), biologically active |
VEGF27-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Human Recombinant VEGF165 Protein (HEK), biologically active |
VEGF27-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2425 |
Human Recombinant VEGF165 Protein (Sf9), biologically active |
VEGF27-R-1000 |
Alpha Diagnostics |
1000 ug |
EUR 9185 |
Human Plasminogen (Plg) Protein (Active) |
20-abx655799 |
Abbexa |
-
EUR 551.00
-
EUR 258.00
-
EUR 1609.00
-
EUR 648.00
-
EUR 411.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Plasminogen (Plg) Protein (Active) |
20-abx655800 |
Abbexa |
-
EUR 551.00
-
EUR 258.00
-
EUR 1609.00
-
EUR 648.00
-
EUR 411.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Recombinant (E.Coli) purified human Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active |
TNFA15-R-10 |
Alpha Diagnostics |
10 ug |
EUR 225 |
Active Plasminogen (Plg) |
4-APB236Hu01 |
Cloud-Clone |
-
EUR 390.30
-
EUR 207.00
-
EUR 1188.64
-
EUR 462.88
-
EUR 825.76
-
EUR 324.00
-
EUR 2821.60
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
Description: Recombinant Human Active Plasminogen (Plg) expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
Active Plasminogen (Plg) |
4-APB236Hu51 |
Cloud-Clone |
-
EUR 390.30
-
EUR 207.00
-
EUR 1188.64
-
EUR 462.88
-
EUR 825.76
-
EUR 324.00
-
EUR 2821.60
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
Description: Recombinant Human Plasminogen expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
Active Plasminogen (Plg) |
4-APB236Ra01 |
Cloud-Clone |
-
EUR 727.20
-
EUR 298.00
-
EUR 2452.00
-
EUR 884.00
-
EUR 1668.00
-
EUR 550.00
-
EUR 5980.00
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
Description: Recombinant Rat Plasminogen expressed in: E.coli |
Human Pancreatic Lipase (partially pure) biologically active |
PLIP15-N |
Alpha Diagnostics |
10 U |
EUR 286 |
Purified Recombinant Human BMP-13 (CDMP-2/GDF-6), Biologically active, Carrier free |
BMP135-R-10 |
Alpha Diagnostics |
10 ug |
EUR 408 |
Purified Recombinant Human BMP-13 (CDMP-2/GDF-6), Biologically active, Carrier free |
BMP135-R-50 |
Alpha Diagnostics |
50 ug |
EUR 895 |
Purified Recombinant Human BMP-14 (CDMP-1/GDF-5), Biologically active, Carrier free |
BMP145-R-10 |
Alpha Diagnostics |
10 ug |
EUR 408 |
Purified Recombinant Human BMP-14 (CDMP-1/GDF-5), Biologically active, Carrier free |
BMP145-R-50 |
Alpha Diagnostics |
50 ug |
EUR 895 |
Rat Plasminogen (Plg) Protein (Active) |
20-abx651431 |
Abbexa |
-
EUR 996.00
-
EUR 356.00
-
EUR 3279.00
-
EUR 1205.00
-
EUR 690.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Recombinant (E.Coli) purified rat Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active |
TNFA25-R-5 |
Alpha Diagnostics |
5 ug |
EUR 225 |
Recombinant (E.Coli) purified mouse Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active |
TNFA35-R-5 |
Alpha Diagnostics |
5 ug |
EUR 225 |
Recombinant (E.Coli) purified porcine Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active |
TNFA36-R-5 |
Alpha Diagnostics |
5 ug |
EUR 225 |
Purified Diphtheria Toxin protein (active) |
DTOX18-N-250 |
Alpha Diagnostics |
250 ug |
EUR 408 |
Recombinant purified, human NFkB-p65 protein, active |
NFKB651-R-5 |
Alpha Diagnostics |
5 ug |
EUR 651 |
Purified, recombinant Human TACE control protein (active) |
TACE15-R-10 |
Alpha Diagnostics |
10 ug |
EUR 712 |
Human Recombinant EG-VEGF Protein (84aa, E. Coli), biologically active |
VEGF36-R-100 |
Alpha Diagnostics |
100 ug |
EUR 1991 |
Human Recombinant EG-VEGF Protein (84aa, E. coli), biologically active |
VEGF36-R-20 |
Alpha Diagnostics |
20 ug |
EUR 773 |
Human Recombinant EG-VEGF Protein (84aa, E. coli), biologically active |
VEGF36-R-5 |
Alpha Diagnostics |
5 ug |
EUR 324 |
Rat Recombinant VEGF152 (VEGF-C) Protein (Sf9), biologically active |
VEGF31-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Rat Recombinant VEGF129 (VEGF-C) Protein (Sf9), biologically active |
VEGF32-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Rat Recombinant VEGF129 (VEGF-C) Protein (Sf9), biologically active |
VEGF32-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2425 |
Rat Recombinant VEGF164 (VEGF-A) Protein (E.Coli), biologically active |
VEGF33-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Rat Recombinant VEGF164 (VEGF-A) Protein (E.Coli), biologically active |
VEGF33-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2478 |
Mouse Recombinant VEGF164 (VEGF-A) Protein (Sf9), biologically active |
VEGF34-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Mouse Recombinant VEGF164 (VEGF-A) Protein (Sf9), biologically active |
VEGF34-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2478 |
Mouse Recombinant VEGF165 (VEGF-A) Protein (E.Coli), biologically active |
VEGF35-R-10 |
Alpha Diagnostics |
10 ug |
EUR 445 |
Mouse Recombinant VEGF165 (VEGF-A) Protein (E.Coli), biologically active |
VEGF35-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2242 |
Active Plasminogen Activator, Tissue (tPA) |
4-APA525Mu01 |
Cloud-Clone |
-
EUR 854.43
-
EUR 332.00
-
EUR 2929.12
-
EUR 1043.04
-
EUR 1986.08
-
EUR 635.00
-
EUR 7172.80
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
Description: Recombinant Mouse Plasminogen Activator, Tissue expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
Human Plasminogen Activator Inhibitor 2 (PAI2) Protein (Active) |
20-abx655801 |
Abbexa |
-
EUR 1080.00
-
EUR 398.00
-
EUR 3599.00
-
EUR 1316.00
-
EUR 746.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Lipase, Human Pancreas (biologically active) antigen grade (.95% pure) |
PLIP15-N-10 |
Alpha Diagnostics |
10 ug |
EUR 286 |
Recombinant (E.Coli) purified human Tumor Necrosis Factor-Alpha Variant (TNF-alpha variant, 151-aa), biologically active |
TNFA16-R-10 |
Alpha Diagnostics |
10 ug |
EUR 225 |
Purified Human Plasminogen protein W. Blot Positive control |
PLMN11-C |
Alpha Diagnostics |
100 ul |
EUR 286 |
Recombinant (E. coli), purified, Mouse beta-Defensin 2 (BD-2/mBD-2) full length protein, biologically active |
MBD25-R-10 |
Alpha Diagnostics |
10 ug |
EUR 457 |
Human Recombinant Transforming Growth Factor-alpha (TGF-alpha), biologically active |
TGFA15-R-100 |
Alpha Diagnostics |
100 ug |
EUR 529 |
Human Recombinant Transforming Growth Factor-alpha (TGF-alpha), biologically active |
TGFA15-R-1000 |
Alpha Diagnostics |
1000 ug |
EUR 3521 |
Human Recombinant Transforming Growth Factor-alpha (TGF-alpha), biologically active |
TGFA15-R-20 |
Alpha Diagnostics |
20 ug |
EUR 225 |
Recombinant (E. coli), purified, Human beta-Defensin 4 (BD-4/hBD-4) full length protein (50 aa), biologically active |
HBD45-R-20 |
Alpha Diagnostics |
20 ug |
EUR 590 |
Recombinant (E. coli), purified, Human beta-Defensin 4 (BD-4/hBD-4) full length protein (50 aa), biologically active |
HBD45-R-5 |
Alpha Diagnostics |
5 ug |
EUR 286 |
Recombinant purified human Akt-1/PKB-alpha protein (active) |
AKT15-R-15 |
Alpha Diagnostics |
15 ug |
EUR 895 |
Recombinant purified, human Akt-2/PKB-beta protein, active |
AKT25-R-10 |
Alpha Diagnostics |
10 ug |
EUR 347 |
Recombinant purified, human Akt-3/PKB-gamma protein, active |
AKT35-R-5 |
Alpha Diagnostics |
5 ug |
EUR 347 |
Recombinant (E.Coli), purified, Human beta-Defensin 3 (BD-3/hBD-3, full length peptide (45 aa), biologically active |
HBD37-R-10 |
Alpha Diagnostics |
10 ug |
EUR 347 |
Recombinant (E.Coli), purified, Human beta-Defensin 3 (BD-3/hBD-3, full length peptide (45 aa), biologically active |
HBD37-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2181 |
Recombinant (E.Coli), purified, Human beta-Defensin 3 (BD-3/hBD-3, full length peptide (45 aa), biologically active |
HBD37-R-1000 |
Alpha Diagnostics |
1000 ug |
EUR 6018 |
Recombinant (E. coli) purified Firefly Luciferase protein, active |
LUCF15-R |
Alpha Diagnostics |
250 ug |
EUR 280 |
Recombinant (E. coli), purified, Human beta-Defensin 1 (BD-1/hBD-1) full length peptide (36 aa), biologically active |
HBD17-R-10 |
Alpha Diagnostics |
10 ug |
EUR 384 |
Recombinant (E. coli), purified, Human beta-Defensin 1 (BD-1/hBD-1) full length peptide (36 aa), biologically active |
HBD17-R-100 |
Alpha Diagnostics |
100 ug |
EUR 1937 |
Recombinant (E. coli), purified, Human beta-Defensin 1 (BD-1/hBD-1) full length peptide (36 aa), biologically active |
HBD17-R-1000 |
Alpha Diagnostics |
1000 ug |
EUR 5531 |
Recombinant (E. coli), purified, Human beta-Defensin 2 (BD-2/hBD-2) full length peptide (41 aa), biologically active |
HBD25-R-10 |
Alpha Diagnostics |
10 ug |
EUR 347 |
Recombinant (E. coli), purified, Human beta-Defensin 2 (BD-2/hBD-2) full length peptide (41 aa), biologically active |
HBD25-R-100 |
Alpha Diagnostics |
100 ug |
EUR 2181 |
Recombinant (E. coli), purified, Human beta-Defensin 2 (BD-2/hBD-2) full length peptide (41 aa), biologically active |
HBD25-R-1000 |
Alpha Diagnostics |
1000 ug |
EUR 6018 |
Purified Human Placenta Dipeptidyl Peptidase IV (DPP4), active |
DPP48-N-1 |
Alpha Diagnostics |
10 ug |
EUR 347 |
Recombinant (E. coli) human placenta growth factor-1 (PLGF-1) Protein (>97%), biologically active |
PLGF15-R-25 |
Alpha Diagnostics |
25 ug |
EUR 529 |
Recombinant (E. coli) human placenta growth factor-1 (PLGF-1) Protein (>97%), biologically active |
PLGF15-R-5 |
Alpha Diagnostics |
5 ug |
EUR 225 |
Human Plasminogen Protein |
abx060920-1mg |
Abbexa |
1 mg |
EUR 384 |
|
Recombinant, purified, Human O6-methylguanine-DNA-Methyl transferase (MGMT) protein (active) |
MGMT15-R-10 |
Alpha Diagnostics |
10 ug |
EUR 651 |
Recombinant, purified, Human O6-methylguanine-DNA-Methyl transferase (MGMT) protein (active) |
MGMT15-R-5 |
Alpha Diagnostics |
5 ug |
EUR 408 |
Recombinant (plant) Human Apotransferrin, Tissue Culture Grade (animal free, biologically active, >95% pure |
TF27-N-100 |
Alpha Diagnostics |
100 mg |
EUR 225 |
Recombinant (plant) Human Apotransferrin, Tissue Culture Grade (animal free, biologically active, >95% pure |
TF27-N-1000 |
Alpha Diagnostics |
100 mg |
EUR 651 |
Recombinant (E.Coli) purified, human Protein Kinase Akt1/PKB alpha (PRKBA/PKB) protein, active |
PAKT18-R-5 |
Alpha Diagnostics |
5 ug |
EUR 529 |
Recombinant purified (E. coli, >80%, GST-tag) human NFkB-p50 protein, active |
NFKB502-R-5 |
Alpha Diagnostics |
5 ug |
EUR 408 |
Recombinant (HEK) Purified human Transferrin receptor (TfR1/CD71) protein (his-tag), active |
TFR19-R-25 |
Alpha Diagnostics |
25 ug |
EUR 286 |
Recombinant purified, human Interleukin-1 alpha (IL-1 alpha), active |
IL1A15-R-10 |
Alpha Diagnostics |
10 ug |
EUR 347 |
Human recombinant purified matrilysin/MMP7 (matrix metalloproteinase 7) biolgoically active |
MMP71-R |
Alpha Diagnostics |
25 ug |
EUR 263 |
Plasminogen protein |
30-AP27 |
Fitzgerald |
1 mg |
EUR 294 |
Description: Purified native Human Plasminogen protein |
Human Plasminogen (Plg) Protein |
20-abx651557 |
Abbexa |
-
EUR 787.00
-
EUR 300.00
-
EUR 2486.00
-
EUR 940.00
-
EUR 551.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Plasminogen (Plg) Protein |
20-abx068558 |
Abbexa |
-
EUR 356.00
-
EUR 217.00
-
EUR 968.00
-
EUR 439.00
-
EUR 286.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Plasminogen (Plg) Protein |
20-abx068560 |
Abbexa |
-
EUR 356.00
-
EUR 217.00
-
EUR 968.00
-
EUR 439.00
-
EUR 286.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Plasminogen |
STA-239 |
Cell Biolabs |
100 µg |
EUR 450 |
Description: - Human Plasminogen protein. 100 µg.
- Provided at a concentration of 1.0 mg/mL
|
Human SOD Protein (Active) |
20-abx060221 |
Abbexa |
-
EUR 314.00
-
EUR 732.00
-
EUR 1295.00
|
|
|
Active Human HSP70 Protein |
SPR-103A |
Stressmarq |
0.05 mg |
EUR 300 |
|
Description: His tagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP70 Protein |
SPR-103B |
Stressmarq |
0.1 mg |
EUR 388 |
|
Description: His tagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP70 Protein |
SPR-103C |
Stressmarq |
2x0.1 mg |
EUR 669 |
|
Description: His tagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP60 Protein |
SPR-104A |
Stressmarq |
0.05 mg |
EUR 231 |
|
Description: His tagged recombinant human HSP60 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP60 Protein |
SPR-104B |
Stressmarq |
0.1 mg |
EUR 387 |
|
Description: His tagged recombinant human HSP60 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP60 Protein |
SPR-104C |
Stressmarq |
2x0.1 mg |
EUR 568 |
|
Description: His tagged recombinant human HSP60 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSC70 Protein |
SPR-106A |
Stressmarq |
0.05 mg |
EUR 236 |
|
Description: His tagged recombinant human HSC70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSC70 Protein |
SPR-106B |
Stressmarq |
0.1 mg |
EUR 310 |
|
Description: His tagged recombinant human HSC70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSC70 Protein |
SPR-106C |
Stressmarq |
2x0.1 mg |
EUR 538 |
|
Description: His tagged recombinant human HSC70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP70 Protein |
SPR-108A |
Stressmarq |
0.05 mg |
EUR 300 |
|
Description: Untagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP70 Protein |
SPR-108B |
Stressmarq |
0.1 mg |
EUR 388 |
|
Description: Untagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP70 Protein |
SPR-108C |
Stressmarq |
2x0.1 mg |
EUR 669 |
|
Description: Untagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP70 Protein |
SPR-115A |
Stressmarq |
0.05 mg |
EUR 346 |
|
Description: His tagged recombinant human HSP70 Protein expressed in Baculovirus/Hi5 cells for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP70 Protein |
SPR-115B |
Stressmarq |
0.1 mg |
EUR 477 |
|
Description: His tagged recombinant human HSP70 Protein expressed in Baculovirus/Hi5 cells for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Active Human HSP70 Protein |
SPR-115C |
Stressmarq |
2x0.1 mg |
EUR 813 |
|
Description: His tagged recombinant human HSP70 Protein expressed in Baculovirus/Hi5 cells for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active). |
Recombinant purified human Akt-1/PKB-alpha protein (PHD deletion 1-116 active) |
AKT16-R |
Alpha Diagnostics |
1 U |
EUR 469 |
Recombinant (E.coli) purified human AKT1(Akt-1/PKB-alpha/RAC-alpha) protein, active |
AKT17-R-10 |
Alpha Diagnostics |
10 ug |
EUR 347 |
Recombinant (E.coli) purified Human Granulocyte Colony Stimulating Factor (GCSF, G-CSF) protein, active |
GCSF16-R |
Alpha Diagnostics |
10 ug |
EUR 384 |
Recombinant (HEK) Human VEGFR1/FLT1 Protein (1-328aa-IgG1-Fc, >95%, ~67 kda, low endotoxin), biologically active |
VEGFR15-R-10 |
Alpha Diagnostics |
10 ug |
EUR 347 |
Recombinant purified human IKKB-beta (Sf9; GST-His-IKK-B), active |
IKKB35-R-5 |
Alpha Diagnostics |
5 ug |
EUR 408 |
Recombinant (HEK) Human VEGFR2/Kdr/FLK1 Protein (1-764aa-IgG-Fc, >95%, ~160 kda, low endotoxin), biologically active |
VEGFR25-R-10 |
Alpha Diagnostics |
10 ug |
EUR 347 |
Active Human Caspases Group I, Active Human |
K241-3-25 |
Biovision |
|
EUR 370 |
Recombinant purified Rat brain Nitric Oxide Synthase (bNOS/NOS-1) protein, active |
bNOS14-R-10 |
Alpha Diagnostics |
5 U |
EUR 263 |
Recombinant purified Human Klotho protein (NS0 cells, His-tag; Alpha form; EC domain), active |
KL16-R |
Alpha Diagnostics |
5 ug |
EUR 286 |
Lys-Plasminogen protein |
30C-CP2108U |
Fitzgerald |
1 mg |
EUR 327 |
Description: Purified native Human Lys-Plasminogen protein |
Recombinant purified human IKB-alpha (E., coli; GST-tag; IKB-alpha), active |
IKBA16-R-10 |
Alpha Diagnostics |
10 ug |
EUR 286 |
TET1 Protein (Active) |
E12002 |
EpiGentek |
10 µg |
EUR 322.6 |
Description: reagents widely cited |
Active BCL2L1 Protein, human recombinant |
7885-10 |
Biovision |
|
EUR 256 |
Active BCL2L1 Protein, human recombinant |
7885-50 |
Biovision |
|
EUR 691 |
Human Arginase (ARG) Protein (Active) |
20-abx651297 |
Abbexa |
-
EUR 982.00
-
EUR 342.00
-
EUR 3209.00
-
EUR 1177.00
-
EUR 676.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Fibronectin (FN) Protein (Active) |
20-abx651335 |
Abbexa |
-
EUR 773.00
-
EUR 300.00
-
EUR 2416.00
-
EUR 913.00
-
EUR 537.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Fibronectin (FN) Protein (Active) |
20-abx651336 |
Abbexa |
-
EUR 829.00
-
EUR 314.00
-
EUR 2666.00
-
EUR 996.00
-
EUR 578.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Leptin (LEP) Protein (Active) |
20-abx651406 |
Abbexa |
-
EUR 523.00
-
EUR 244.00
-
EUR 1497.00
-
EUR 606.00
-
EUR 384.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Myostatin (MSTN) Protein (Active) |
20-abx651418 |
Abbexa |
-
EUR 1094.00
-
EUR 398.00
-
EUR 3613.00
-
EUR 1316.00
-
EUR 746.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Neuraminidase (NEU) Protein (Active) |
20-abx651421 |
Abbexa |
-
EUR 1121.00
-
EUR 411.00
-
EUR 3724.00
-
EUR 1358.00
-
EUR 759.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Neuraminidase (NEU) Protein (Active) |
20-abx651422 |
Abbexa |
-
EUR 1121.00
-
EUR 411.00
-
EUR 3724.00
-
EUR 1358.00
-
EUR 759.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Osteopontin (SPP1) Protein (Active) |
20-abx651425 |
Abbexa |
-
EUR 1121.00
-
EUR 411.00
-
EUR 3724.00
-
EUR 1358.00
-
EUR 759.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Erythropoietin (EPO) Protein (Active) |
20-abx652296 |
Abbexa |
-
EUR 1790.00
-
EUR 578.00
-
EUR 6258.00
-
EUR 2193.00
-
EUR 1177.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Adenosylhomocysteinase (AHCY) Protein (Active) |
20-abx655555 |
Abbexa |
-
EUR 1135.00
-
EUR 411.00
-
EUR 3780.00
-
EUR 1372.00
-
EUR 773.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Amphiregulin (AREG) Protein (Active) |
20-abx655557 |
Abbexa |
-
EUR 732.00
-
EUR 286.00
-
EUR 2305.00
-
EUR 885.00
-
EUR 523.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Betacellulin (bTC) Protein (Active) |
20-abx655563 |
Abbexa |
-
EUR 1024.00
-
EUR 356.00
-
EUR 3376.00
-
EUR 1233.00
-
EUR 704.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Calreticulin (CRT) Protein (Active) |
20-abx655571 |
Abbexa |
-
EUR 1066.00
-
EUR 398.00
-
EUR 3530.00
-
EUR 1288.00
-
EUR 732.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Endostatin (COL18A1) Protein (Active) |
20-abx655607 |
Abbexa |
-
EUR 913.00
-
EUR 328.00
-
EUR 2973.00
-
EUR 1107.00
-
EUR 634.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Epigen (EPG) Protein (Active) |
20-abx655610 |
Abbexa |
-
EUR 913.00
-
EUR 328.00
-
EUR 2973.00
-
EUR 1107.00
-
EUR 634.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Erythropoietin (EPO) Protein (Active) |
20-abx655612 |
Abbexa |
-
EUR 982.00
-
EUR 342.00
-
EUR 3209.00
-
EUR 1177.00
-
EUR 676.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Hemojuvelin (HJV) Protein (Active) |
20-abx655665 |
Abbexa |
-
EUR 815.00
-
EUR 314.00
-
EUR 2569.00
-
EUR 968.00
-
EUR 565.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Hepcidin (Hepc) Protein (Active) |
20-abx655669 |
Abbexa |
-
EUR 634.00
-
EUR 272.00
-
EUR 1929.00
-
EUR 759.00
-
EUR 467.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Lymphotactin (Lptn) Protein (Active) |
20-abx655748 |
Abbexa |
-
EUR 1135.00
-
EUR 411.00
-
EUR 3808.00
-
EUR 1386.00
-
EUR 773.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Midkine (MK) Protein (Active) |
20-abx655772 |
Abbexa |
-
EUR 1177.00
-
EUR 425.00
-
EUR 3947.00
-
EUR 1428.00
-
EUR 801.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Myostatin (MSTN) Protein (Active) |
20-abx655781 |
Abbexa |
-
EUR 1094.00
-
EUR 398.00
-
EUR 3613.00
-
EUR 1316.00
-
EUR 746.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Nephronectin (NPNT) Protein (Active) |
20-abx655783 |
Abbexa |
-
EUR 1094.00
-
EUR 398.00
-
EUR 3613.00
-
EUR 1316.00
-
EUR 746.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Neuroserpin (NSP) Protein (Active) |
20-abx655786 |
Abbexa |
-
EUR 996.00
-
EUR 356.00
-
EUR 3293.00
-
EUR 1205.00
-
EUR 690.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Noggin (NOG) Protein (Active) |
20-abx655789 |
Abbexa |
-
EUR 773.00
-
EUR 300.00
-
EUR 2416.00
-
EUR 913.00
-
EUR 537.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Osteonectin (ON) Protein (Active) |
20-abx655792 |
Abbexa |
-
EUR 704.00
-
EUR 286.00
-
EUR 2165.00
-
EUR 829.00
-
EUR 495.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
The truth is, scientific developments at such an accelerated tempo have already negatively affected our cultural, moral, and authorized values and our capability to harness the alternatives and face the risks posed by such developments. As a matter of reality, science appears to persistently outpace public morals, ethics and policymaking, which requires a excessive diploma of warning and customary solutions.