Brain organoids: human 3D models to investigate neuronal circuits assembly, function and dysfunction

Brain organoids: human 3D models to investigate neuronal circuits assembly, function and dysfunction

The human mind is characterised by a rare complexity of neuronal and nonneuronal cell varieties, wired collectively into patterned neuronal circuits, which characterize the anatomical substrates for the execution of high-order¬†cognitive¬†features. Mind circuits’ improvement and performance is metabolically supported by an intricate community of selectively permeable blood vessels and finely tuned by short-range interactions...